As mentioned above, bifidobacteria degrade hexose sugars through a particular metabolic pathway, termed the “bifid shunt”, where the fructose-6-phosphoketolase enzyme (EC 4.1.2.2) plays a key role (Fig. 2) . This enzyme is considered to be a taxonomic marker for the family of Bifidobacteriaceae .

Dec 3, 2019 · Bifidobacteria degrade the hexose sugars glucose and fructose through a unique pathway named “bifid shunt”, which is centred on the key enzyme fructose-6-phosphate phosphoketolase 9.

Dec 9, 2021 · However, all bifidobacteria use a characteristic hexose fermentation pathway, known as the bifid shunt, for carbon dissimilation 4, 7, due to the lack of 6-phosphofructokinase (EC 2.7.1.11),...

Feb 17, 2017 · Instead, bifidobacteria possess a unique fermentation pathway known as the “bifid shunt” which relies on the enzyme phosphoketolase to metabolize Fructose-6-phosphate (F6P) [3, 14 – 19].

Bifidobacteria lack a number of key enzymes involved in the Emden-Meyerhof Parnas (EMP) pathway, instead, bifidobacteria metabolize hexose sugars through a metabolic pathway named the “bifid shunt” which is centered around the key enzyme, fructose-6-phosphoketolase (EC 4.1.2.2) (Figure 1; De Vries and Stouthamer, 1967; De Vuyst et al., 2014).

In bifidobacteria, phosphoketolase (PKT) plays a key role in the central hexose fermentation pathway called “bifid shunt.”

Jan 1, 2019 · To obtain higher carbon yields, we constructed a carbon conservation pathway named EP-bifido pathway in Escherichia coli by combining Embden-Meyerhof-Parnas Pathway, Pentose Phosphate Pathway and “bifid shunt”, to generate high yield acetyl-CoA from glucose.

Feb 17, 2017 · Members from the order Bifidobacteriales, which include many species exhibiting health promoting effects, differ from all other organisms in using a unique pathway for carbohydrate metabolism, known as the "bifid shunt", which utilizes the enzyme phosphoketolase (PK) to carry out the phosphorolysis …

Feb 22, 2022 · In bifidobacteria, phosphoketolase (PKT) plays a key role in the central hexose fermentation pathway called "bifid shunt." The three-dimensional structure of PKT from Bifidobacterium longum with co-enzyme thiamine diphosphate (ThDpp) was determined at 2.1 Å resolution by cryo-EM single-particle anal …

Bifidobacteria are a minor fraction of the human colon microbiota with interesting properties for carbohydrate degradation. Monosaccharides such as glucose and fructose are degraded through the bifid shunt, a dedicated pathway involving phosphoketolase activity.