Mar 28, 2025 · B4GALT5 (Beta-1,4-Galactosyltransferase 5) is a Protein Coding gene. Diseases associated with B4GALT5 include Gm1 Gangliosidosis . Among its related pathways are Sphingolipid metabolism and Keratan sulfate biosynthesis .

Beta-1,4-galactosyltransferase 5 is an enzyme that in humans is encoded by the B4GALT5 gene. [5] [6] [7] This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes.

Results demonstrated B4GalT5 downregulation improved insulin resistance by promoting adipogenic commitment and decreasing M1 macrophage infiltration. beta-1,4-GalT-V gene/protein expression is specifically increased in colorectal cancer, compared to visibly normal tissue.

Feb 7, 2018 · We showed that the expression of β1, 4-galactosyltransferase 5 (B4GalT5) was positively correlated with diabetes and obesity. In vivo, B4GalT5 knockdown in subcutaneous adipose tissue...

Jun 6, 2013 · The results revealed that B4GALT1 and B4GALT5 were highly expressed in four MDR cells and patients, altered levels of B4GALT1 and B4GALT5 were responsible for changed drug-resistant phenotype...

Dec 10, 2024 · Clinical resource with information about B4GALT5, Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu, and available tests.

Mar 5, 2024 · B4GALT1 and B4GALT5, two members of B4GALT gene family, are involved in the development of multidrug resistance of human leukemia cells. Title: B4GALT family mediates the multidrug resistance of human leukemia cells by regulating the hedgehog pathway and the expression of p-glycoprotein and multidrug resistance-associated protein 1.

B4GALT5 is a prognostic marker in Liver hepatocellular carcinoma, Pancreatic adenocarcinoma

Gene B4GALT5 is associated with 26 reactions in 5 different subsystems, and present in the compartments: Cytosol, Endoplasmic reticulum, Golgi apparatus. Provided by metabolicatlas.org Pathway / Subsystem

Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes.