B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. [1] They function in the humoral immunity component of the adaptive immune system. [1] B cells produce antibody molecules which may be either secreted or inserted into the plasma membrane where they serve as a part of B-cell receptors. [2]

Feb 1, 2023 · What are B cells (B lymphocytes)? B cells are a type of white blood cell that makes infection-fighting proteins called antibodies. B cells are an important part of your immune system, your body’s defense against harmful pathogens (viruses, bacteria and parasites) that enter your body and make you sick.

Oct 4, 2020 · What are B Cells? B cells are lymphocytes – a type of white blood cell. They are the result of multipotential cell differentiation in the bone marrow. Every blood cell is derived from a single cell type – the pluripotent hematopoietic stem cell. This stem cell changes or differentiates into two forms within the bone marrow.

Oct 13, 2024 · B cells or B lymphocytes (bursa-derived cells) are essential components of adaptive immune response, primarily responsible for humoral immunity in mammals. B-cell production in humans is a lifelong process that starts in the fetal liver, intrauterine, and bone marrow after birth.[1]

Apr 9, 2021 · B cell or B lymphocyte is a type of lymphocyte (white blood cells) involved in the humoral immunity of the adaptive immune system as they differentiate into plasma and produce antibodies. Besides, B cells are also considered professional antigen-presenting cells as these can detect antigens present on the surface of bacteria and viruses.

Mar 12, 2025 · B cell, one of the two types of lymphocytes (the other is the T cells). All lymphocytes begin their development in the bone marrow. B cells are involved in so-called humoral immunity. On encountering a foreign substance (antigen), the B cell differentiates into a plasma cell, which secretes

Nov 10, 2021 · Without T lymphocytes, also called T cells, every exposure could be life-threatening. T cells can wipe out infected or cancerous cells. They also direct the immune response by helping B lymphocytes to eliminate invading pathogens. B cells create antibodies. B lymphocytes, also called B cells, create a type of protein called an antibody.

B cells have a positive role in priming adaptive CD4+ T cells, but not CD8+ T cells. The magnitude of CD4+ T-cell responses is reduced upon pathogen challenge in B-cell deficient or depleted mice. B cells are also able to dampen T-cell driven immune responses, giving rise to the concept of regulatory B cells (Bregs).

When naïve or memory B cells are activated by antigen (and helper T cells—not shown), they proliferate and differentiate into effector cells. The effector cells produce and secrete antibodies with a unique antigen-binding (more...)

Memory and plasma B cells produce antibodies including immunoglobulin (Ig) IgM, IgG, and IgE. This page describes the development of mature B cell types and tools to study B cells including cell culture, immunoassays, and cell markers for immunophenotyping.