ADAMTS7 - Wikipedia
A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAMTS7) is an enzyme that in humans is encoded by the ADAMTS7 gene on chromosome 15. [1] It is ubiquitously …
ADAMTS7 Gene - GeneCards | ATS7 Protein | ATS7 Antibody
Mar 28, 2025 · ADAMTS7 (ADAM Metallopeptidase With Thrombospondin Type 1 Motif 7) is a Protein Coding gene. Diseases associated with ADAMTS7 include Arthritis and Weill …
Role of ADAM and ADAMTS proteases in pathological tissue …
Dec 9, 2023 · In this review, we describe that catalytic activities of ADAM10 and ADAMTS7, like shedding of ephrin-B2 by ADAM10 and degradation of COMP by ADAMTS7, have been …
ADAMTS proteins in human disorders - PMC - PubMed Central …
ADAMTS7 is strongly associated with coronary artery disease and promotes atherosclerosis. Autoantibodies to ADAMTS13 lead to a platelet coagulopathy, thrombotic thrombocytopenic …
The Function and Roles of ADAMTS-7 in Inflammatory Diseases
ADAMTS-7 is a member of ADAMTS family and plays a crucial role in the pathogenesis of arthritis. Overexpression of ADAMTS-7 gene promotes the breakdown of cartilage oligomeric …
ADAMTS-7 Modulates Atherosclerotic Plaque Formation by …
Sep 7, 2023 · ADAMTS-7, which is induced in unstable atherosclerotic plaques, decreases TIMP-1 stability reducing its inhibitory effect on MMP-9, which is known to promote collagen …
Coronary Disease Association With ADAMTS7 Is Due to Protease …
Jun 28, 2021 · ADAMTS7 is a secreted metalloproteinase and complex proteoglycan; yet, the mechanism linking ADAMTS7 to CAD risk remains unresolved. To investigate the role of …
ADAMTS7: A Novel Therapeutic Target in Atherosclerosis - PMC
Genome-wide association studies have repeatedly linked the metalloproteinase ADAMTS7 to coronary artery disease. Here we aim to highlight recent findings surrounding the human …
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 …
Feb 8, 2025 · ADATMS-7 regulates the focal adhesion kinase signaling and promotes invasiveness of trophoblasts in early pregnancy. Effect of a coronary-heart-disease-associated …
Biochemistry and physiological functions of ADAMTS7 …
ADAMTS7 is an intriguing enzyme with potentially widespread roles in a variety of physiological and pathophysiological events. ADAMTS7 appears to bind and cleave COMP, PGRN, and α2 …