Tyrosine-protein kinase ABL1 also known as ABL1 is a protein that, in humans, is encoded by the ABL1 gene (previous symbol ABL) located on chromosome 9.

When mutated, oncogenes have the potential to cause normal cells to become cancerous. A genetic rearrangement (translocation) involving the gene causes a type of cancer of blood …

Mar 28, 2025 · ABL1 (ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase) is a Protein Coding gene. Diseases associated with ABL1 include Congenital Heart Defects And Skeletal …

Apr 7, 2025 · This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to …

Without question, ABL capabilities are encoded by its gene sequence and that molecular blueprint designs this kinase to be regulated by subcellular location-dependent interactions with …

The Abelson (ABL) family of nonreceptor tyrosine kinases, ABL1 and ABL2, transduces diverse extracellular signals to protein networks that control proliferation, survival, migration, and …

Sep 14, 2016 · The ABL1 gene provides instructions for making a protein involved in many processes in cells throughout the body. The ABL1 protein functions as a kinase, which is an …

Jul 11, 2013 · ABL kinases regulate the function of invadopodia, actin-rich structures that remodel the extracellular matrix during cancer cell invasion. ABL kinases are required for cancer cell …

Abl kinases are prototypic cytoplasmic tyrosine kinases and are involved in a variety of chromosomal aberrations in different cancers. This causes the expression of Abl fusion …

The ABL protein, alternatively referred to as Abelson proto-oncogene, is a tyrosine kinase protein that assumes a pivotal function in cellular signalling and regulation [11]. The ABL1 gene, …