PFOB NPs are new potential UCAs that persist for long periods in the circulatory system, possess a relatively stable echogenic response without increasing the background signal and exhibit lower acoustic attenuation than commercial UCAs.

In mechanical endovascular thrombectomy (MET) for acute basilar artery occlusion (ABAO) in the elderly, navigating a guide catheter via the femoral artery may be difficult due to the approach route’s significant tortuosity. To resolve this problem, ...

Aug 8, 2010 · Here we report the first atomistic structural details of a perfluorooctylbromide-based (PFOB-based) nanoemulsion particle (NEP) with a 1-palmitoyl-2-oleoyl-phosphatidylcholine (POPC) lipid emulsifier. Newly developed PFOB force field parameters were used in molecular dynamics simulations to model the PFOB-NEP interface in a planar configuration.

Fluorine-19 magnetic resonance imaging (19 F MRI) with intravenously applied perfluorooctyl bromide-nanoemulsions (PFOB-NE) has proven its feasibility to visualize inflammatory processes in experimental disease models.

May 30, 2019 · Fluorine-19 magnetic resonance imaging (19 F MRI) with intravenously applied perfluorooctyl bromide-nanoemulsions (PFOB-NE) has proven its feasibility to visualize inflammatory processes in experimental disease models.

Currently, perfluorodecalin (PFD) and perfluorooctyl bromide (PFOB) are the majorly used perfluorocarbons in the field of artificial oxygen carriers. So far, in our investigations only PFD has been employed as core material of albumin-derived artificial oxygen carriers (A-AOCs).

Jan 8, 2025 · Polyethylene glycol (PEG)-coated microsized artificial oxygen carriers (AOCs) with a perfluorooctyl bromide (PFOB) core and poly(lactide-co-caprolactone) (PLC) shell were successfully fabricated using Shirasu porous glass (SPG) membrane emulsification.

Jul 31, 2021 · Here, an innovative platform, perfluorooctyl bromide (PFOB) nanoemulsions holding MnO 2 nanoparticles (MBP), was developed to orchestrate cancer immunotherapy, serving as a theranostic nanoagent for MRI/CT dual-modality imaging and advanced ICD.

Perfluorooctylbromide (PFOB) is an emulsion-forming compound with one bromine atom per molecule [41–43]. The attenuation coefficient of bromine is lower than that of iodine so that the efficacy of PFOB with only one absorbing atom compared to three for “conventional” X-ray contrast agents is much smaller.

【Introduction】Acute basilar artery occlusion (ABAO) is associated with high mortality rate and poor outcome in patients treated conservatively. We treated patients with ABAO with aggressive reperfusion therapy in combination with several endovascular modalities.