Apr 4, 2017 · Role of Asn 563 /Asn 618 in FL-GP processing and incorporation. We have shown that N563Q/N618Q mutations synergistically reduce ΔMLD-GP processing and incorporation …

NGSs (Asn257, Asn268, Asn296, Asn563, and Asn618) were mutated (N257Q–N618Q), GP 1 became undetectable in cells and virions (Fig. 2, A and B, lane 23); when Asn563 and Asn618 …

Sep 29, 2019 · Although GP 2 contains two N-glycosylation sites, Asn 563 and Asn 618, Wang et al. demonstrated that EBOV GP expression does not depend on GP 2.

Mar 3, 2016 · Conversely, Asn-566 (site 2) and Asn-618 (site 3) of E-cadherin are not occupied with N-glycans, suggesting that these N-glycosylation sites are not critical for controlling the …

Further analysis uncovered that Asn 563 and Asn 618 regulate GP processing, demannosylation, oligomerization, and conformation. Consequently, these two NGSs are required for GP …

Jul 20, 2015 · As shown in Figure 2b, the potential N-glycosylation site Asn-618 (site 3) displays a low ASA value, suggesting a low probability of being N-glycosylated.

Oct 6, 2023 · although Asn (563) and Asn (618) are not required for EBOV GP expression, they synergistically regulate its maturation, which determines its functionality.

Apr 7, 2017 · Further analysis uncovered that Asn 563 and Asn 618 regulate GP processing, demannosylation, oligomerization, and conformation. Consequently, these two NGSs are …

values at Asn residue indicate a reduced probability of N-glycans attachment. As shown in Figure 2b, the potential N-glycosylation site Asn-618 (site 3) displays a low ASA value, suggesting a...