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  1. Arachidonate 5-lipoxygenase - Wikipedia

    Arachidonate 5-lipoxygenase is a member of the lipoxygenase family of enzymes. It transforms essential fatty acids (EFA) substrates into leukotrienes as well as a wide range of other …

  2. ALOX5 Gene - GeneCards | LOX5 Protein | LOX5 Antibody

    Mar 28, 2025 · ALOX5 (Arachidonate 5-Lipoxygenase) is a Protein Coding gene. Diseases associated with ALOX5 include Asthma and Atherosclerosis. Among its related pathways are …

  3. ALOX5 arachidonate 5-lipoxygenase [ (human)] - National Center …

    Feb 8, 2025 · ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma. Role of ALOX5 in non-small cell lung cancer: A potential therapeutic …

  4. Emerging Roles of 5-Lipoxygenase Phosphorylation in …

    ALOX5 is the rate-limiting enzyme for the biosynthesis of leukotrienes, a family of proinflammatory lipid mediators derived from arachidonic acid. ALOX5 also make great contributions to …

  5. 5‐Lipoxygenase Gene Variants Are Not Associated With …

    Mar 29, 2016 · The arachidonate 5‐lipoxygenase enzyme plays a crucial role in mediating inflammation to maintain homeostasis, yet certain allelic variants of the 5‐lipoxygenase gene, …

  6. 5-lipoxygenase pathway and its downstream cysteinyl ... - PubMed

    5-lipoxygenase (ALOX5) is an enzyme involved in arachidonic acid (AA) metabolism, a metabolic pathway in which cysteinyl leukotrienes (CysLTs) are the resultant metabolites.

  7. ALOX5 arachidonate 5-lipoxygenase [ Homo sapiens (human) ]

    Mar 4, 2025 · Title: ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma. Role of ALOX5 in non-small cell lung cancer: A potential …

  8. ALOX5AP Gene - GeneCards | AL5AP Protein | AL5AP Antibody

    Mar 28, 2025 · ALOX5AP (Arachidonate 5-Lipoxygenase Activating Protein) is a Protein Coding gene. Diseases associated with ALOX5AP include Stroke, Ischemic and Frontotemporal …

  9. Entry - *152390 - ARACHIDONATE 5-LIPOXYGENASE; ALOX5

    Alox5 deficiency caused impairment of the function of LSCs by affecting differentiation, cell division, and survival of long-term LSCs. This resulted in a depletion of LSCs and a failure of …

  10. ALOX5 (Arachidonate 5-Lipoxygenase).

    Jul 1, 2006 · The ALOX5 gene encodes a member of the lipoxygenase gene family, 5-LOX, which catalyzes the synthesis of leukotrienes (LT) from arachidonic acid. Leukotrienes are …

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