A549 cells were isolated from the lung tissue of a White, 58-year-old male with lung cancer. This cell line can be used in cancer, immuno-oncology, and toxicology research.

A549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al. through the removal and culturing of cancerous lung tissue in the explanted tumor of a 58-year-old caucasian male. [1]

The A549 cell lines are the most commonly used human non-small cell lung cancer cell lines for both basic research and drug discovery. In this article, we will cover every topic about this cell line, ranging from general information to research applications.

May 1, 2016 · Today a large number of human non-small cell lung cancer cell lines exist that are being used for both basic research and drug discovery. One commonly used line is A549, an epithelial carcinoma derived from a 58 year old male patient, known to be KRAS mutant and EGFR wild type.

Characteristics: Expresses HPRT1 at the surface of the cell membrane (PubMed= 28408844). Virology: Highly susceptible to infection by Zika virus (ZIKV) (PubMed= 29468137).

An A549 cell is a type of human alveolar basal epithelial cell that is squamous in nature and plays a role in the diffusion of substances across the alveoli of the lungs. AI generated definition based on: Electroporation-Based Therapies for Cancer, 2014

The A549 cell line, emblematic of human non-small cell lung cancer, originates from the adenocarcinoma subtype within the alveolar epithelial cells. These cells offer a versatile model for a wide array of investigations in cancer biology, toxicology, and immuno-oncology.

The A549 cell line is a widely used human lung adenocarcinoma cell line that was derived from a primary lung tumor. A549 cells are highly proliferative and have been used in a wide variety of research applications.

The A549 cells are characterized as a hypotriploid human alveolar basal epithelial cells and are widely used as an in vitro model for type II pulmonary epithelial cells as well as a model of lung adenocarcinoma. These cells grow adherently in monolayer and are …

A549 cells are a well-characterized standard among the human lung carcinoma/alveolar cell lines used in molecular biology. The A549 cells stored at the NIH were tested under the guidance of the FDA’s cGMP regulations and may be suitable for producing adenoviruses that can be used in clinical trials and analyzing adenoviral-based therapies and ...