Oct 28, 2024 · The face of the giant panda sign in neuroimaging refers to the appearance of the midbrain, when the red nucleus and substantia nigra are surrounded by high T2 signal in the tegmentum. It is classically seen in Wilson disease, although whenever the white matter is diffusely abnormal in the region a similar appearance will be perceived.

The face of the giant panda sign, panda sign of the midbrain or double-panda sign is a characteristic "panda's face" appearance in magnetic resonance imaging (MRI) images of people with Wilson's disease.

The “Face of the Giant Panda” and the “Panda Cub” signs are classically described neuroimaging appearances seen in patients with Wilson’s disease. A number of conditions may demonstrate the “Face of the Giant Panda” sign and should be considered depending on the clinical scenario.

Oct 13, 2003 · The MRI abnormalities in the midbrain reveal the “face of the giant panda” sign that is characteristic of Wilson’s disease.1 In addition, a second miniature “panda face” can be seen in the high signal abnormality in the pons .

Oct 29, 2013 · The most common radiological abnormalities described in Wilson’s disease are changes in signal intensity of grey and white matter especially T2W hyperintensities in putamen (particularly lateral side), globus pallidus, thalamus, caudate, subthalamic tegmental region, red nucleus, substantia nigra and dentate nucleus. 2 Atrophy of the head of ...

Jan 28, 2024 · The double panda sign refers to the combination of the face of the giant panda and face of the miniature panda (cub of the giant panda) seen on T2 weighted images of midbrain and pons respectively, most commonly seen in Wilson disease.

Oct 23, 2024 · T2-weighted MRI brain demonstrating a mesencephalic “panda sign,” with high signal intensity in the tegmentum.

Apr 15, 2014 · The midbrain ‘face of giant panda sign’ is due to high signal in the tegmentum, normal signals in the red nuclei and lateral portion of the pars reticulata of the substantia nigra, and hypointensity of the superior colliculus.

Mar 16, 2009 · The midbrain “panda sign” is due to high signal in the tegmentum, normal signals in the red nuclei and lateral portion of the pars reticulata of the substantia nigra, and hypointensity of the superior colliculus.

Jan 1, 2019 · The pons face of the "miniature-panda" sign consists of relative hypointensity of the central tegmental tracts (eyes) contrasting with the hyperintensity of the aqueduct opening into the...