4-hydroxybenzaldehyde is a hydroxybenzaldehyde that is benzaldehyde substituted with a hydroxy group at position C-4. It has a role as a plant metabolite, a mouse metabolite and an …

2.5 Effects of 4-HBd on BBB protection and neural repair in a rat IS model. To evaluate the role of 4-HBd in BBB stabilization and neuroprotection, the MCAO/R model was replicated, and rats …

Aim: 4-Hydroxybenzaldehyde (4-HBd) is used for the treatment of headaches, dizziness, and convulsions. The objective of this study was to characterize the pharmacokinetics of 4-HBd in …

Jan 31, 2025 · The active ingredient of Gastrodia elata, 4-hydroxybenzaldehyde (4-HBd), can rapidly enter the brain and undergo massive oxidation to produce the metabolite 4 …

Mar 1, 2025 · In our previous research, we confirmed the significant anti-IS effects of Gastrodia elata, with its principal active component, 4-hydroxybenzaldehyde (4-HBd), capable of …

4-Hydroxybenzaldehyde (4-HBd) is the main active ingredient in Gastrodia elata Blume (Orchidaceae), a sap-rophytic herb used for the treatment of headaches, dizziness, and …

4-Hydroxybutyryl-coenzyme A (CoA) dehydratase (4HBD) from Clostridium aminobutyricum catalyzes the reversible dehydration of 4-hydroxybutyryl-CoA to crotonyl-CoA and the …

Nov 24, 2023 · Pharmacokinetics of 4-Hydroxybenzaldehyde in Normal and Cerebral Ischemia-Reperfusion Injury Rats Based on Microdialysis Technique. 1 Europe PMC requires Javascript …

Ischemic stroke (IS) results from the sudden disruption of cerebral blood flow and can lead to brain cell death and neurological deficits. Middle cerebral artery occlusion/reperfusion …

Dec 1, 2017 · Aim: To verify the mechanisms underlying the protective effects of the 4-hydroxybenzaldehyde (4-HBd) on cerebral ischemia/reperfusion in vivo and in vitro. Methods: …