Feb 3, 2015 · Here, we generated miR-23a∽27a∽24-2 and/or miR-23b∽27b∽24-1 cluster bi-allelic knockout ESC clones and elucidated that the miRNA clusters were indispensable for ESC differentiation in vitro and in vivo. To our knowledge, this is the first study to identify miRNAs function using CRISPR/Cas9 in ESCs.

Feb 3, 2015 · Among them, miR-27a and miR-24, restrained by c-Myc in ESC, exert their roles of silencing self-renewal through directly targeting several important pluripotency-associated factors, such as Oct4, Foxo1 and Smads.

Dec 17, 2014 · miR-27/24 in ESCs leads to serious deficiency in ESC differentiation in vitro and in vivo. Moreover, depleting of them in mouse embry-onic fibroblasts can evidently promote somatic cell reprogramming. Altogether, our findings uncover the essential role of miR-27 and miR-24 in ESC differentiation and also demonstrate novel

High-Performance Cooling Fans for HOBBYWING ESCs come in various sizes and power voltages. Each unit is checked and approved via ISO 9001 Quality Control procedure.

Oct 15, 2023 · miR-27a plays a crucial role in endometrial fibrosis. It regulates TGFβ1-induced EMT, migration, oxidative stress, and apoptosis in ESCs. Additionally, miR-27a impacts mitophagy through PINK1 suppression upon H₂O₂ induction.

Serum microRNA-27a expression, association with severity of coronary atherosclerosis in coronary heart disease patients. Session: Poster Session 1 - Thrombosis, platelets, coagulation and coronary artery disease. Topic: Pathophysiology and Mechanisms, Other. Speaker: Professor E. Baranova (Saint Petersburg, RU) About the speaker.

Serum microRNA-27a expression in patients with acute coronary syndrome without ST-segment elevation undergoing percutaneous coronary intervention

Mar 3, 2015 · Altogether, our findings uncover the essential role of miR‐27 and miR‐24 in ESC differentiation and also demonstrate novel microRNAs responsible for ESC differentiation. MicroRNAs play important roles in controlling the embryonic stem cell (ESC) state.

May 5, 2014 · For Sale Himax HA2825 2700kv Inrunner & BL37/II 27A ESC Electric Power Systems (FS/W)

The 2.7A 1S Dual Way Micro Brushed ESC is a compact and lightweight electronic speed controller. Here are its key specifications: – Model: Brushed – Current: 3.3V-6V, with a long-distance running current of 2.7A and a peak current of 10A – Size: 20x9mm – Weight: 2g