Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene. [5] eIF4B has been shown to interact with and stimulate the activity of eIF4A and bind to …

Mar 28, 2025 · EIF4B (Eukaryotic Translation Initiation Factor 4B) is a Protein Coding gene. Diseases associated with EIF4B include Mouth Disease and Schinzel-Giedion Midface …

Yeast eIF4B (Tif3) consists of an N-terminal domain, followed by a domain with seven repeat regions, an RNA recognition motif and a C-terminal domain (Figure 1C). eIF4B stimulates …

Jan 29, 2024 · The structure identifies the interaction of eIF4B with the entry site bound eIF4A, providing insight into its role in regulating this second eIF4A rather than eIF4F during scanning.

Oct 10, 2024 · This study reveals how the intrinsically disordered region of eIF4B governs its transition from monomers to oligomers and condensed droplets, providing key insights into …

Sep 8, 2024 · Title: eIF4B enhances ATF4 expression and contributes to cellular adaptation to asparagine limitation in BRAF-mutated A375 melanoma. Long noncoding RNA GMAN …

Oct 10, 2010 · In this review we will analyze the bulk of data describing eIF4B and its role in cell survival and proliferation. Recent studies have shown that eIF4B is phosphorylated and …

We have investigated the role of eukaryotic initiation factor 4B (eIF4B) in this process and identify 10-fold more RNA binding sites for eIF4B in tumour cells from patients with diffuse large B-cell …

eIF4B is the RSK downstream effector responsible for elevated Lamgamma2 as well as MYC protein in neoplastic epithelial cells. The protein level of eukaryotic translation initiation factor …

In this study, we show that eIF4G differs from eIFiso4G in that it contains two distinct interaction domains for the poly (A) binding protein (PABP) and eIF4B but is similar to eIFiso4G in having …