In organic chemistry, a thiol (/ ˈ θ aɪ ɒ l /; [1] from Ancient Greek θεῖον (theion) ' sulfur ' [2]), or thiol derivative, is any organosulfur compound of the form R−SH, where R represents an alkyl or other organic substituent.

A thiol is a compound which contains an SH functional group. The -SH group itself is called a mercapto group. A disulfide is a compound containing an -S-S- linkage.

Jul 5, 2015 · Thi ols are more nucleophilic than alcohols, and thiol ates are more nucleophilic than alkoxides. Since nucleophilicity is measured by reaction rate , that means that these sulfur nucleophiles tend to react faster with typical electrophiles (like …

Thiol, any of a class of organic chemical compounds similar to the alcohols and phenols but containing a sulfur atom in place of the oxygen atom. Thiols are among the odorous principles in the scent of skunks and of freshly chopped onions; their presence in petroleum and natural gas is

Sep 30, 2024 · Treatment of a thiol with a base, such as NaH, gives the corresponding thiolate ion (RS –), which undergoes reaction with a primary or secondary alkyl halide to give a sulfide. The reaction occurs by an S N 2 mechanism, analogous to …

Thiols and thiol-derived compounds have several important roles in biology. As thiolate, RS −, they can function as bases, as ligands (e.g., in the binding of metals, as in hemoglobin), and as agents for the transfer of acetyl groups (e.g., in acetyl CoA) in lipid biosynthesis.

Before addressing protein-associated thiol chemistry and biology, this review begins with an introduction to thiol-containing small molecules encountered in biological systems. Small molecule thiols in biology

Feb 28, 2024 · What is a Thiol? A thiol, in its most fundamental definition, is a chemical compound characterized by the presence of a sulfhydryl group (-SH). This molecular arrangement comprises a sulfur atom bonded to a hydrogen atom.

Thiols, also called mercaptans, are sulfur analogs of alcohols. They are named by the same system used for alcohols, with the suffix -thiol used in plac...

The meaning of THIOL is any of various compounds having the general formula RSH which are analogous to alcohols but in which sulfur replaces the oxygen of the hydroxyl group and which have disagreeable odors.