A positive result for SSA (Ro) or SSB (La) antibodies is highly suggestive of a diagnosis of Sjogren syndrome. The presence of isolated anti-SS-B/La antibody has low positive predictive value of Sjogren syndrome.

Aug 20, 2023 · If a rheumatologist suspects that a patient has Sjogren's based on their signs and symptoms, they will typically order a blood test for SSA as a first step. If the test comes back positive for SSA, they usually arrive at a diagnosis of Sjogren’s.

Jul 20, 2024 · Detailed guide to SSA-Ro antibodies, critical for diagnosing Sjögren's syndrome and systemic lupus erythematosus (SLE).

Mar 21, 2021 · Anti-SSA is a positive blood test in many lupus and Sjogren’s disease patients. It is also called anti-Ro antibody. Systemic lupus erythematosus (SLE) who are anti-SSA positive have an increased risk for some lupus complications like sun-sensitive rashes, subacute cutaneous lupus, and neonatal lupus.

Aids in the diagnosis of Sjögren's syndrome (especially with vasculitis) and lupus patients with Sjögren's overlap syndrome. SS-A (Ro) is found in 60% to 70% of patients with Sjögren's syndrome and 30% to 40% of patients with SLE. SS-B (La) is found in 50% to 60% of Sjögren's syndrome and 10% to 15% of SLE.

What Do My SSA Blood Test Results Mean? The SSA blood test may not be specific enough on its own to provide a diagnosis of SLE. Even with the signs and symptoms present of an autoimmune disorder, there is up to a 70% error rate in the results of this test. A positive result is only seen in about 30% of those who have systemic lupus.

Sjögren's antibody (SS-B) is present only if Sjögren's antibody (SS-A) is also detected. The presence of both antibodies (SS-A and SS-B) strengthen the diagnosis of Sjögren's Syndrome and conveys prognostic information. Reference ranges are provided as general guidance only.

Anti-Ro (SS-A) is an autoantibody associated with SLE or Sjögren’s syndrome. What is Sjögren’s syndrome? - Sjögren’s syndrome is an autoimmune disorder in which the body's immune system mistakenly reacts to the tissue in glands that produce moisture, such as tear and salivary glands.

People with lupus who have a negative ANA test may have anti-Ro/SSA or antiphospholipid antibodies. In people with a positive ANA, more tests are usually performed to check for other antibodies that can help to confirm the diagnosis.

Feb 11, 2019 · anti-SSA often appears before anti-SSB. Interpretation: Anti-SSA levels may be elevated in the following conditions: Sjögren’s syndrome: 60%-70% of cases; Systemic lupus erythematous (SLE): 25% of cases; Both anti-SSA and Anti-SSA are usually absent in secondary Sjögren’s syndrome.