Interleukin 17 family (IL17 family) is a family of pro-inflammatory cystine knot cytokines. [2] . They are produced by a group of T helper cell known as T helper 17 cell in response to their …

Interleukin-17 (IL-17, also known as IL-17A) is a key cytokine that links T cell activation to neutrophil mobilization and activation. As such, IL-17 can mediate protective innate immunity …

IL-17 has come a long way in 25 years: from an obscure cytokine belonging to a poorly-understood cytokine subfamily to a signature of a key T helper cell population and a key …

Mar 22, 2024 · IL-17 inhibitors block this cytokine’s inflammatory pathways and are used to treat psoriasis and psoriatic arthritis. IL-17 inhibitors belong to a family of biologic drugs called …

Oct 11, 2023 · Interleukin 17 (IL-17) is an important cytokine that has several roles in host defense responses against mucosal infections; additionally, it is a primary pathologic cytokine …

In this review, we outline the current knowledge of signal transduction and known physiological activities of IL-17 family cytokines. We will highlight in particular the current understanding of …

Apr 16, 2019 · Here, we discuss the functions of the IL-17 family, with a focus on the balance between the pathogenic and protective roles of IL-17 in cancer and autoimmune disease, …

The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A-F, plays crucial roles in host defense against microbial organisms and in the development of inflammatory diseases.

Interleukin-17A is a protein that in humans is encoded by the IL17A gene. In rodents, IL-17A used to be referred to as CTLA8, after the similarity with a viral gene (O40633). [5][6] The protein …

May 18, 2017 · Increased understanding of the biology of interleukin 17 (IL-17) has revealed that this cytokine is a central player in immunity at the sites most exposed to microorganisms. …