Varicella (chickenpox) is an acute, highly contagious disease caused by varicella-zoster virus (VZV), a member of the herpesvirus family. Only one serotype of VZV is known, and humans are the only reservoir.

Jul 19, 2013 · A systematic post-licensure review of the varicella vaccine Varivax® (Merck) safety in the United States of America (USA) was presented in preparation for an update of the WHO position paper on varicella vaccines. 3 A summary of the 2011 US Institute of Medicine (IOM) report, 4 a literature review from December 2010 to October 2012, and review of key post …

Varicella-zoster virus (VZV) causes both varicella (chickenpox) by primary infection and herpes zoster (HZ or shingles) by endogenous reactivation from latency. VZV circulates worldwide. Acquisition of infection tends to be at a younger age in temperate countries (> 90% infected by adolescence in absence of vaccination programme), compared to ...

Jul 9, 2014 · It integrates new information related to global prevalence and burden of disease caused by varicella and herpes zoster (HZ) with data on the safety, immunogenicity, efficacy and effectiveness of varicella and HZ vaccines and the duration of protection conferred by these vaccines, as well as cost effectiveness considerations.

varicella disease of any severity and 90.7% effective against moderate/severe varicella, while 2 doses of a combined vaccine were 94.9% effective against disease of any severity and 99.5% effective against severe/moderate disease.

Nov 10, 2008 · Overview . This module is part of the WHO series The Immunological Basis for Immunization, which was initially developed in 1993 as a set of eight modules, comprising one module on general immunology and seven modules each devoted to one of the vaccines recommended for the Expanded Programme on Immunization, i.e. vaccines against …

Sep 5, 2018 · varicella incidence remains high, most varicella-like rashes among recently immunized persons will still be due to wild-type varicella. Modified varicella in a vaccinated person. Modified varicella, also known as breakthrough varicella, is varicella due to wild-type virus that occurs in vaccinated people (> 42 days after vaccination).

Aug 26, 2024 · HIV testing should be offered to adults with mpox, and children as appropriate. Diagnostic tests for other conditions should be considered where feasible, for example, varicella zoster virus (VZV), syphilis and herpes. Treatment and vaccination . The goal of treating mpox is to take care of the rash, manage pain and prevent complications.

Dec 11, 2024 · Herpes simplex virus (HSV), known as herpes, is a common infection that can cause painful blisters or ulcers. It primarily spreads by skin-to-skin contact. It is treatable but not curable. There are two types of herpes simplex virus. Type 1 (HSV-1) mostly spreads by oral contact and causes infections in or around the mouth (oral herpes or cold ...

Varicella Zoster Virus Vaccine Information sheet. 13 June 2012 | Publication. Download (305.1 kB) WHO Team.