PROX1 - Wikipedia
Prospero homeobox protein 1 is a protein that in humans is encoded by the PROX1 gene. [5] [6] The Prox1 gene is critical for the development of multiple tissues. Prox1 activity is necessary …
PROX1 Gene - GeneCards | PROX1 Protein | PROX1 Antibody
Mar 30, 2025 · PROX1 (Prospero Homeobox 1) is a Protein Coding gene. Diseases associated with PROX1 include Lymphangioma and Generalized Lymphatic Anomaly. Among its related …
Active repression of cell fate plasticity by PROX1 safeguards ...
Feb 13, 2025 · Our findings provide evidence for PROX1 as a hepatocyte-specific safeguard and support a model where cell-type-specific repressors actively suppress plasticity throughout life …
The Role of PROX1 in Neoplasia: A Key Player Often Overlooked
The human PROX1 gene (Prospero homeobox gene 1) is a member of the homeobox transcription factor family. PROX1 plays a key role in the development of the lymphatic system …
PROX1 prospero homeobox 1 [ Homo sapiens (human) ]
Feb 8, 2025 · Title: Prox1 Suppresses Proliferation and Drug Resistance of Retinoblastoma Cells via Targeting Notch1. PROX1 interaction with alpha-SMA-rich cancer-associated fibroblasts …
PROX1 protein expression summary - The Human Protein Atlas
PROX1 is a prognostic marker in Thyroid carcinoma Cancer specificity i Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, …
Transcription factor PROX1: its role in development and cancer
The homeobox gene PROX1 is critical for organ development during embryogenesis. The Drosophila homologue, known as prospero has been shown to act as a tumor suppressor by …
Prospero-related homeobox 1 gene (Prox1) is regulated by ... - PNAS
Here we identified the prospero-related homeodomain transcription factor Prox1 as a target of β-catenin–TCF/LEF signaling in vitro and in vivo. Prox1 overexpression enhanced neuronal …
PROX1 is a transcriptional regulator of MMP14 | Scientific Reports …
Jun 22, 2018 · Here, we show that PROX1 suppresses the transcription of MMP14, a metalloprotease involved in angiogenesis and cancer invasion, by binding and suppressing …
PROX1 is a novel pathway-specific prognostic biomarker for high …
PROX1 is a transcription factor with an essential role in embryonic development and determination of cell fate. In addition, PROX1 has been ascribed suppressive as well as …