eIF1A plays an important role in start codon recognition; however, its molecular contacts with eIF5 are unknown. Using nuclear magnetic resonance, we unveil eIF1A’s binding surface on the ...

aInstitute of Medical Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK bInstitute of Applied Health Sciences, School of Medicine, Medical Sciences and ...

eIF1A and eIF5 were overexpressed in E. coli and purified essentially according to the literature. Some hydrophobic chromatography media were tested if they can be used for purification of the wheat ...

One such target is Basic leucine zipper and W2 domains 2 (BZW2), also known as translation initiation regulator eIF5-mimic protein 1 (5MP1), a member of the basic‐region leucine zipper (bZIP) ...

We found that its treatment modulated expression of several molecules of translational complex such as RPL (RPL9, RPL11, RPL15), RPS (RPSA, RPS9, RPS16, RPS20), and translation initiation factors ...

A schematic representation of the role of eIF1 and eIF5 in regulating stringency of start codon selection in eukaryotes. (Left) mRNA with the mORF AUG start codon in suboptimal context (mAUG*). (Right ...

Reduction of PTENε in response to eIF2A knockdown. Hela cells were infected with lentivirus expressing eIF2A shRNA, eIF5 shRNA, or scramble shRNA separately. The knockdown of eIF2A or eIF5 was ...

Heart failure (HF) is the most common long-term complication of acute myocardial infarction (MI). Understanding plasma proteins associated with post-MI HF and their gene expression may identify new ...

Finally, correlation analysis of RHEB and EIF5 expression with clinicopathological parameters of HCC patients revealed that the circRNA-100338, RHEB, and EIF5 were indicators of poor prognosis in ...