It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

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A promising new treatment to combat "undruggable" cancers has been green-lit for a human trial in 2025. It's hoped the novel ...

A world-first clinical trial targeting cancers that are currently undruggable will begin later this year, led by a research team from The Australian ...

DelveInsight’s, “Diffuse Large B-Cell Lymphoma Pipeline Insight 2025” report provides comprehensive insights about 70+ ...

The U.S Marine Corps has deployed its newly fielded anti-drone Marine Air Defense Integrated System (MADIS) for this year’s Balikatan 2025 exercise in the Philippines, where it will undergo its ...

Arms Control Association's Daryl Kimball discusses the future of Iran's nuclear program and former INS Commissioner Doris Meissner from the Migration Policy Institute discusses ICE workplace raids.

MYC amplification is frequently observed in approximately 50% of human cancers, rendering it a highly desired anticancer target. Given the challenge of direct pharmacological inhibiting of MYC, ...

c-MYC controls global gene expression and regulates cell proliferation, cell differentiation, cell cycle, metabolism and apoptosis. According to some estimates, MYC is dysregulated in ≈70% of human ...

HEATR1 contains a canonical Myc-binding E-box (CACGTG) in its promoter and has been proposed as a MYC transcriptional target in a genome-wide analysis of MYC-binding sites in Burkitt lymphoma cell ...