imageimageOocytes plays a central role in the success of reproduction, yet the phosphorylation dynamics during mammalian oocyte development remain poorly understood. This resource article describes ...

This highlights the importance of ZFP57 as an important factor for the maintenance of imprinted methylation at gDMRs. 5′-TGC(5mC)GC-3′ is the canonical binding motif for ZFP57 (Quenneville et al., ...

rs3131875 (ZFP57/HLA-F: odds ratio [OR], 1.97; P =1.66×10 −39) rs1611163 (upstream of HLA-G: OR, 0.54; P =1.39×10 −32) rs9357092 (ZNR1ASP: OR, 2.04; P =8.74×10 −48), ...

rs3131875 (ZFP57/HLA-F: odds ratio [OR], 1.97; P =1.66×10 −39)rs1611163 (upstream of HLA-G: OR, 0.54; P =1.39×10 −32) ; rs9357092 (ZNR1ASP: OR, 2.04; P =8.74×10 −48), rs2596506 (HLA-B ...

DNA sequencing The risk score can improve upon EBV-based screening, according to researchers. A polygenic risk score (PRS) can identify patients at high risk of developing nasopharyngeal carcinoma ...

ZFP57, HOXB1, HOXD4, NR2F2, MEIS1, and MSX2 were already described when the cases of same histology were compared with controls. Interestingly, the DMR close to HOXB1 was found hypomethylated and the ...

Quenneville S, Verde G, Corsinotti A, Kapopoulou A, Jakobsson J, Offner S, Baglivo I, Pedone PV, Grimaldi G, Riccio A et al (2011) In embryonic stem cells, ZFP57/KAP1 recognize a methylated ...

This study provides further proof for ZFP57 as a master regulator of genomic imprinting since it maintains DNA methylation at most known imprinted regions and regulates allelic expression of the ...

ZFP57 in rat models has been shown to alter stress vulnerability, and so epigenetic changes in this gene region appear to govern an important aspect of PTSD development and recovery.