lactis expressing XCL1 – Production of feasible well-tolerated vector to deliver biological active XCL1 at a mucosal level [60] CCL21 vaults Lung 3LL tumor cells Enhanced leukocyte infiltration ...

Biochemists in the US have found limits to what AlphaFold, the usually highly accurate protein structure prediction artificial intelligence system developed by Google DeepMind, can do. Lauren Porter’s ...

The origins of cancer vaccines date back to the 1800s. Since then, there have been significant efforts to generate vaccines against solid and hematologic malignancies using a variety of platforms. To ...

The study published online in Brain, Behavior, and Immunity on Feb. 29, reported that cytokine XCL1 produced by maternal immune cells can function as a pregnancy hormone and is required for the proper ...

"Using mouse models, we found that circulating XCL1 normally remained at the same low pre-pregnancy level throughout gestation except for a short rise and fall in the middle period," said ...

The following is a summary of “Improvements in immune/melanocyte biomarkers with JAK3/TEC family kinase inhibitor ritlecitinib in vitiligo,” published in the January 2024 issue of Allergy & Immunology ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. T‐cell infiltrates in muscle biopsies of ...

Chemokines belong to a family of proteins called the cytokines and are involved in initiating and guiding the recruitment and migration of immune cells to sites of infection or damage. Chemokines ...

XCR1- binds to the XC chemokines, XCL1 and XCL2 Structural similarities and differences between chemokine receptors Around 19 types of chemokine receptor have been identified to date and they are ...

Upon stimulation with CD19-3T3 cells or anti-CD3/CD28 beads, a large population of cells express high level of CSF2 and other cytokines, including IFNG, IL2, IL13, CCL3/CCL4, and XCL1/XCL2.

To improve our understanding, we here evaluate molecular and cellular requirements for CD4 + T cell and antibody polarization after immunization with Xcl1-fusion vaccines that specifically target ...