South Korean scientists at KAIST have discovered a method to transform cancer cells into healthy cells. The technique uses an ...

Researchers have discovered that the genes related to extracellular matrix (ECM) and the Wnt signaling pathway characterize ...

Mr. Høiland is already well-acquainted with Allarity's mission and operations, having served as a strategic consultant to the Company since October 2024.

Acute myelogenous leukemia, or AML, remains one of the most aggressive blood cancers. Each year, around 44,000 people in the U.S. and Europe are diagnosed. For many, the road ahead is grim. Despite ...

Just a few weeks after conception, stem cells are already orchestrating the future structure of the human brain. A new Yale-led study shows that, early in development, molecular “traffic cops” known ...

Ovarian cancer (OC) remains the deadliest gynecologic malignancy, with platinum-based chemotherapies such as carboplatin ...

To explore Wnt pathway actions, the researchers focused on how Wnt signals regulate genes, a process mediated by proteins involved in DNA binding, as well as In addition to its essential role in ...

Sierra and Gold’s approach combined orthologous (similar) genes into clusters and used a novel statistical method to look for enrichment of particular genes. However, their analysis provided little ...

The Wnt pathway is hijacked in this way in more than 80 per cent of colorectal cancers and some pancreatic cancers, ... they discovered that a second mutation in another gene, ...

image: Abnormality of the Wnt pathway induces microsatellite instability (MSI) and regulates immune response in colorectal cancer. view more . Credit: Genes & Diseases ...

The Wnt signaling pathway, a system present in living organisms, plays a pivotal role in cell growth, differentiation, and migration. It has a long history dating back to 1982, when the first Wnt ...

In the absence of Wnt signaling (B), the destruction complex breaks down β-catenin and inhibits gene transcription. Several other proteins also contribute to the inhibition of Wnt signaling.