whole exome sequencing did not reveal somatic mutations in components of the Wnt pathway (online supplemental figure 3A). This implies that DGC cells residing outside of the Wnt niche rely on ...

Wnt and Fzd expression at TS19: Summerhurst K., Stark M., Sharpe J., Davidson D., Murphy P. (2008) 3D representation of of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic ...

School of Medicine, Nankai University, Tianjin 300071, P. R. China Department of Orthopedic Surgery, Institute of Orthopedics, The Fourth Medical Center of Chinese PLA General Hospital; Beijing Key ...

that synergizes with Wnt-3a ligand in the activation of Wnt/β-catenin signal transduction. Through affinity chromatography and subsequent functional assays, we showed that QS11 binds and inhibits the ...

3A hair specifically is a fairly common curl type, though it's not always easy to identify because of its similarity to other curl patterns in the type 3 category. If you're curious to know if you ...

FIGURE 4. Wnt 3a/β-catenin reduce the expression of cytoplasmic Cys-C through transnuclear action, and reduce the occurrence of mitochondrial oxidative stress injury induced via Cys-C/ROS, inhibited ...

We also updated the limb bud Fgfr2b image (Figure 4C’). 3. Wnt3a expression. If Wnt 3a is expressed in the mesenchyme why don't you see it in the single cell data in Figure 3B, B'? I don't see any ...

Section of Receptor Biology & Signaling, Dept. Physiology & Pharmacology, Karolinska Institutet, S-17165, Stockholm, Sweden ...

The mystery of two functionally redundant Axin genes in all vertebrates can now be explained by the demonstration that they form a nested proteostatic and transcriptional feedback system that confers ...

Successful disruption of individual ORFs was confirmed by sequencing, Supplementary Figures 2A,D, 3A–E. To corroborate our findings, we established a panel of HEK293 cells devoid of critical ...

Transient expression of YFP-β-catenin was performed using PolyJET (SignaGen, Israel). For generating Wnt3a conditioned medium (CM) and mock CM, L-Wnt-3A and L- mouse fibroblast cells were grown in ...