Warfarin was associated with more risk than apixaban (Eliquis; 55.38 vs 21.42 per 1,000 person-years, HR 2.60, 95% CI ...

Veterans Affairs (VA) Health Administration guidelines on COX-2 inhibitors allow their use as an alternative to traditional NSAIDs for pain management in patients taking warfarin; however ...

DOACs are as effective and safe as warfarin—sometimes more so—and are far more straightforward to take. Dr. Mitchell said, "For example, apixaban (a DOAC) has a lower risk of significant ...

Vitamin K-inhibiting anticoagulants, especially warfarin, have become standard ... significant benefit with warfarin and other vitamin K inhibitors. The generalizability of these randomized ...

In the matched cohort, DOAC use (versus warfarin) was associated with a lower rate of ischemic ... antiplatelet agents, proton‐pump inhibitors, and statins), and measures of health care use (eg, ...

Adenosine deaminase inhibitors blocking inosine and hypoxanthine production abolished the inhibition of L-arginine on osteoclastogenesis in vitro and in vivo. Altered arginine levels were also found ...