U1 snRNA is an interesting biological tool for splicing correction and regulation of gene expression. However, U1 snRNA has never been chemically synthesized. In this study, the first chemical ...

Before this study, it was known that LUC7 proteins associate with U1 snRNA, but the exact function wasn't clear. There are three different LUC7 proteins in human cells, ...

Before this study, it was known that LUC7 proteins associate with U1 snRNA, but the exact function wasn't clear. There are three different LUC7 proteins in human cells, ...

Before this study, it was known that LUC7 proteins associate with U1 snRNA, but the exact function wasn't clear. There are three different LUC7 proteins in human cells, ...

Before this study, it was known that LUC7 proteins associate with U1 snRNA, but the exact function wasn’t clear. There are three different LUC7 proteins in human cells, ...

The spliceosome, a complex of proteins and small nuclear RNAs (snRNAs), forms on introns. Initially, an snRNA called U1 snRNA binds to the 5′ splice site at the start of the intron. It was previously ...

It was easy to miss Apple’s new U1 chip because it wasn’t highlighted during the debut appearance of the iPhone 11 lineup, but it is present in all three of the new phones.Apple’s ...

Using this plasmid, the splicing is driven by the exogenous U1 snRNA and the effects of mutations on stem‐loop 3 were investigated. The mutations C 98–101 A and G 108–110 U were introduced into pG3‐U1 ...

This flexibility is combined with the precision of the message reading frame. Apart from intron-termini GU_AG and the branchpoint A, the most conserved are the exon-end guanine and +5G of the intron ...

We have found U1 small nuclear ribonucleoprotein (snRNP) alteration and RNA splicing deficiency in Alzheimer’s disease. U1 snRNP components (U1-70K, U1A, and snRNA) are depleted from nuclei and form ...

SnRNA U1, U2, U5 levels were detected by quantitative real-time polymerase chain reaction (qRT-PCR). Exosomes were isolated by ultracentrifugation and identified by qNano. Results: TEP U1, U2, U5 ...