eLife23d
A VgrG2b fragment cleaved by caspase-11/4 promotes Pseudomonas aeruginosa infection through suppressing the NLRP3 inflammasome
This valuable study on Pseudomonas subverting host immunity identifies a new immune evasion strategy. There is solid evidence for the cleavage of VgrG2B by Caspase 11 and the generation of fragments ...
C&EN1mon
Trilobatin, a Naturally Occurring GPR158 Ligand, Alleviates Depressive-like Behavior by Promoting Mitophagy
School of Pharmacy, Faculty of Medicine, Macau University of Science and Technology, Taipa, Macau SAR 999078, China Key Laboratory of Basic Pharmacology of Ministry of Education and Joint ...
Frontiers1y
Targeting mitophagy for depression amelioration: a novel therapeutic strategy
This was accompanied by increased protein expressions of LC3BII/I, P62, and TOM20 (Jin et al., 2023 ... Abnormal expression of key proteins such as PINK1, Parkin, LC3B, and P62 indicates a breakdown ...
Medscape2y
The journal of physical chemistry. B, Materials, surfaces, interfaces & biophysical
Self-aggregation properties of ionic liquid 1,3-didecyl-2-methylimidazolium chloride in aqueous solution: from spheres to cylinders to bilayers.
Frontiers3y
SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy Impairment
The entry process of dsRNA might be mediated by Tom20 as observed by reduced mitochondrial localization of SARS-CoV-2 dsRNA in Tom20 knockdown cells. Importantly, decreased mitochondrial localization ...