In a search for the kinase responsible for PDK1 Y163 phosphorylation, TIE1 was identified as a potential candidate. TIE1, a receptor tyrosine kinase, was found to be upregulated by ING5 and ...

In a search for the kinase responsible for PDK1 Y163 phosphorylation, TIE1 was identified as a potential candidate. TIE1, a receptor tyrosine kinase, was found to be upregulated by ING5 and ...

Previous research has pointed to mutations in the genes PIEZO1, ANGPT2 and TIE1 as potential culprits responsible for lymphedema. In the current study, investigators studied mice missing these ...

After applying Bonferroni correction, we found that the risk of ADHD was increased by brain proteins GMPPB, NAA80, HYI, CISD2, and HYI, TIE1 in CSF and plasma. Proteins GMPPB, NAA80, ICA1L, CISD2, ...

They identified that the binding of Polydom with another protein, Tie1, is important for lymphatic cell migration in lymphangiogenesis. "We know that another protein, a receptor known as Tie1 ...

We have shown that TIE2 is required for vein development while little is known about its homologue TIE1 (tyrosine kinase with immunoglobulin-like and EGF [epithelial growth factor]-like domains 1) in ...

This study presents strong and compelling evidence that the extra-cellular matrix protein SVEP-1 interacts with the TIE1 receptor to promote aspects of lymphangiogenesis that are independent of ...

In homeostatic conditions, both Ang-1 and Ang-2 activate Tie2 signaling and induce vascular stabilization in a Tie1-dependent manner. However, inflammatory processes induce Tie1 cleavage, leading to ...

Correct "xxx-584" or more detail on what this means. We Thank the reviewer for pointing out this typo. This refers to the deletion made in tie1, in the region corresponding to nucleotides 485-584 of ...

Genes associated with endothelial senescence and leukocyte adhesion, including SERPINE1 (PAI-1), CXCL8 (IL8), CXCL1, CXCL2, ICAM-2, and TIE1, were significantly upregulated in B3 microvessels after ...