A novel blood-based assay could transform coeliac disease diagnosis, particularly for patients already on a gluten-free diet.

The active substance of Attrogy, diflunisal, stabilizes the TTR tetramer, preventing its dissociation into the TTR monomers that are responsible for the disease pathology.

A tetramer-guided epitope mapping (TGEM) approach tested 68 possible epitopes from gE and identified 14 that were MHC class II-restricted, meaning that they are recognized by CD4⁺ T cells in the ...

An influenza virus with surface glycoprotein spikes hemagglutinin (HA, trimer, red) and neuraminidase (NA, tetramer, purple). [ KATERYNA KON/SCIENCE PHOTO LIBRARY/1386012927/Science Photo Library ...

GluN1-N2A-N2B tri-heteromeric tetramer highlighted the functional integration of GluN2A and GluN2B subunits in vivo. Its structure showed a distinct assembly and asymmetric architecture.

Using computational simulations, they proposed that the tetramer was an intermediate structure that is processed to produce the final pentameric structure. Interestingly, ...

The potential for personalized cancer treatment is fueling the need to identify T cell responses against neoantigens and other cancer-specific epitopes for the success of immunotherapy. Continuous ...

Structural and thermodynamic insights into antibody light chain tetramer formation through 3D domain swapping. Nature Communications, 2023; 14 (1) DOI: 10.1038/s41467-023-43443-4; ...

However, such experiments would then form the basis of reversal of both LRRK2 activation and synuclein tetramer formation; this could be dissected out, to some degree, using the SCD inhibitor reported ...

Regarding the purity of Human HLA-G RIIPRHLQL Tetramer Protein (Cat. No. HLG-H52E9), this is over 85% and the molecular weight of this protein is around 228-278 kDa verified by SEC-MALS.