Tenascin-C is a well-studied biomarker known for its high overexpression in the stroma of most solid cancers. Tenascin-W, the least studied member of the family, is highly expressed in the stroma ...

Tenascin R triggered the prevalence of the protein CD68, which drives acute inflammation. Both proteins are also known to limit the movement of oligodendrocytes.

Researchers at Ruhr-Universität Bochum have been studying the role of the two proteins tenascin C and tenascin R in multiple sclerosis. In this disease, cells of the immune system destroy the ...

Studies by scientists at the German Cancer Research Center (DKFZ) and HI-STEM have found that metastatic breast cancer cells exploit macrophages, a type of immune cell, to promote the settlement ...

"These macrophages, which often reside in the vicinity of the lung blood vessels, are activated by tenascin, an extracellular matrix protein produced by breast cancer cells," explains Tsunaki ...

In human endothelial cells as well as in human and mouse aortae, unidirectional laminar flow but not disturbed flow strongly increased endothelial expression of the extracellular matrix protein TN-X ...

Tenascin C is a potential biomarker of cancer-associated fibroblasts and has been significantly associated with poor prognosis in patients with prostate cancer. However, the effects of Tenascin C in ...

The role of the protein tenascin-C, an extracellular matrix component, in retinal ischaemia was investigated in mice by researchers from Ruhr-Universität Bochum (RUB). They showed that tenascin-C ...

The role of the protein tenascin-C, an extracellular matrix component, in retinal ischaemia was investigated in mice by researchers from Ruhr-Universität Bochum (RUB). They showed that tenascin-C ...