During embryo development, Wnt cooperates with a protein called TBX3, which controls the development of the legs, arms and heart. In other words, if the TBX3 gene is damaged by mutations ...

"Women showed higher levels of TBX3 and HCN1, which are two key genes that help drive faster heart rhythms," said Ning Li, MD, PhD, Ohio State research assistant professor and co-author of the study.

"Women showed higher levels of TBX3 and HCN1, which are two key genes that help drive faster heart rhythms," said Ning Li, MD, PhD, Ohio State research assistant professor and co-author of the study.

"Women showed higher levels of TBX3 and HCN1, which are two key genes that help drive faster heart rhythms," said Ning Li, MD, PhD, Ohio State research assistant professor and co-author of the study.

Our research reveals that the transcription factor TBX3, long recognized for its role in limb and heart embryogenesis, becomes aberrantly present in colorectal cancers (CRC). In this extraneous ...

The work presented is important for our understanding of the development of the cardiac conduction system and its regulation by T-box transcription factors. The conclusions are supported by convincing ...

In China, Ningqiang ponies have unique genetic traits and show moderate inbreeding, distinguishing them from other local horse breeds Scientists identified key genes, including TBX3, that determine ...

Although remarkable looking, it is not looks that have scientists excited about this "walking" fish with six legs. Instead, it is what was proven about evolution that was the real thrill. Sea robins ...

“New things are built from old friends,” Kingsley said, pointing out that the tbx3 gene has played a role in fin and limb development for hundreds of millions of years. “There’s a bunch of ...

Tbx3 proteins have previously been found to play a key role in the development of hind legs in vertebrates, including humans, and sea robins appear to be no different. But the protein had an extra ...

The gene TBX3, whose gene expression is shown here in green, assists with early limb formation by restricting the expression of other genes (here in red and blue) in early limb buds of mice. Image ...

Phase 3 trial evaluating setmelanotide in pediatric patients ages 2-<6yo (N=12) over 52 weeks achieved primary endpoint Setmelanotide achieved 3.04 mean reduction in BMI-Z score and 18.4 percent mean ...