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13 patients dosed with TTX-MC138 across four dose levels; no significant toxicities reported. PK/PD data shows predictable dose-response and miRNA-10b target engagement in 5 of 6 patients at lower ...
(D) Example traces showing the optically-evoked EPSP (upper panels) and slow component of the IPSP (lower panels) was maintained following application of TTX/4AP. (E) Normalized peak amplitude of the ...
TransCode also reported that two additional patients in Cohort 4 are scheduled to receive TTX-MC138. The therapeutic candidate being evaluated, TTX-MC138, is TransCode's lead candidate designed to ...
TTX Company (TTX) on March 18 announced the retirement of Vice President & Chief Financial Officer (CFO) Vicki Dudley, effective April 1, 2025, and Vice President & Chief Human Resources Officer (CHRO ...
TransCode Therapeutics (RNAZ) announced that Cohort 3 of its Phase 1 clinical trial enrolled three patients and all have been dosed with TTX-MC138, its lead candidate. TTX-MC138 is a first-in ...
Cybersecurity company Hack The Box has launched a tabletop exercise (TTX) for its online training platform, that uses an artificial intelligence model to create an unlimited series of practice ...
Patients currently remain on study for continued treatment with TTX-MC138 No significant safety or dose limiting toxicities reported TTX-MC138, an antisense oligonucleotide conjugated to TransCode ...
TTX is a structured yet low-pressure environment where participants rehearse their roles in response to, for example, a compromised email account, a service outage or a potential breach attempt during ...
At the center of the deal was TTX-080, a novel checkpoint inhibitor targeting HLA-G, that was on the precipice of a phase 1 trial at the time the deal was announced. The trial has been ongoing for ...
Dashed lines indicate the timing of the large disynaptic component of the responses (i, indirect), and the small monosynaptic response (d, direct), isolated in TTX-4AP. See also Figure 6—figure ...
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