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The results in the publication include: Biochemical Target Inhibition: ATI-2138 covalently inhibits ITK, a TCR-activated Tec family kinase, more potently than the other Tec kinase family members ...

“ATI-2138 potently and selectively blocks both ITK and JAK3. Through this mechanism, ATI-2138 has been shown in preclinical studies to effectively inhibit Th1, Th2 and Th17 cell ...

The advent of T-cell receptor (TCR) sequencing offers a transformative lens to unravel these challenges, spotlighting tumor-immune interactions and adaptive immune mechanisms pivotal to advancing ...

For those looking for an even showier Elantra N, the new TCR Edition has you covered. Hyundai says the special edition of the performance sedan is "inspired by its multiple race and championship ...

Adoptive therapies based on CAR/TCR T cells—that is, T cells with an engineered chimeric antigen receptor (CAR) or a T-cell receptor (TCR)—have shown promise for a range of cancers ...

[Keith Chambers / Science Photo Library / Getty Images] Chimeric antigen receptor (CAR) T-cell and T-cell receptor (TCR) T-cell therapies are promising treatments for a range of cancers ...

Interleukin 2 inducible T cell kinase (ITK) plays a role in both T cell receptor (TCR) signaling and T helper cell differentiation. ITK-/- mice exhibit defects in Th2 differentiation while retaining ...

SEOUL, South Korea — Kumho Tire Co. Inc. has secured the naming rights for the TCR World Tour for touring cars, a global championship that overlaps with seven national and regional TCR series on four ...

LONDON — Sedan road-racing series in Europe running under Touring Car Championship (TCR) regulations are switching to race tires built by South Korea's Kumho Tire Co. Inc., according to the TCR's ...