CD127, the cell surface protein IL‐7Rα encoded by IL7R, defines a heterogeneous subset of cytokine‐producing ILCs, with developmental and functional parallels to CD4 + helper T cells (Artis & Spits, ...

Figure 1.Tbx21 mRNA expression increases at the neuromuscular junction (NMJ) in young adult wildtype (WT) mice following peripheral nerve transection and immediate repair (A).Representative image ...

The Tbx21 Cre mouse expresses cre selectively in M/T cells, and the Rosa26 DTA mouse expresses diphtheria toxin (DTA) upon cre-mediated recombination, which triggers the death of M/T cells . To count ...

In particular, Mettl3 binds Tbx21 transcript and sustains its stability, allowing normal production of T-bet protein, which in return boosts CD8 T cell effector differentiation.

Please use one of the following formats to cite this article in your essay, paper or report: APA. Sai Lomte, Tarun. (2023, August 10). Study explores the diverse expression patterns of T cell ...

Molecular studies of PTCL-NOS have defined at least two subtypes, GATA3 and TBX21, the former having a poorer prognosis, but how this guides therapeutics remains unknown. Outside of ALCL, there is a ...

Background: Autoimmunity is increasingly recognized as a key contributing factor in heart muscle diseases. The functional features of cardiac autoimmunity in humans remain undefined because of the ...

Since the enrichment of CX3CR1 and TBX21 in the NK1 subset suggests augmented maturation of NK cells, we next conducted pseudo-temporal analysis with Monocle2. The pseudo-time analysis ordered cells ...

The heterogeneous T-cell neoplasm known as peripheral T-cell lymphomas (PTCLs) is frequently linked to epigenetic instability. For a study, researchers sought to determine novel molecular subtypes of ...

PTCL, NOS may be subdivided into PTCL-GATA3 and PTCL-TBX21 on the basis of upregulation of GATA3 or TBX21 and their associated genes. Although PTCL-TBX21 is generally associated with more favorable ...

Researchers from the Mount Sinai Health System, NY, present the first genome-wide study to investigate the cause of a rare but severe inflammatory syndrome in children following SARS-CoV-2 infection.