Shorla Oncology (‘Shorla’), a U.S.-Ireland specialty pharmaceutical company, today announced the launch of a dedicated sales force and market access t ...

Despite the massive desmoplastic reaction characteristic for pancreatic ductal adenocarcinoma ... that otherwise fail in patients with pancreatic ductal adenocarcinoma. Stromal depletion or ...

An increase in ECM protein concentration, increased matrix crosslinking or parallel reorientation of matrix fibrils within a stromal matrix can stiffen a tissue locally to alter cell growth or ...

Sorafenib-plus-capecitabine is associated with a high incidence of grade 3 hand–foot syndrome/skin reaction (45%). Sorafenib-plus-paclitaxel demonstrated a statistically significant improvement ...

In 2023, 253,341 laboratory animals were used at the Max Planck Institutes. This figure includes 95,715 animals that were used to obtain organ or tissue samples and were not exposed to any stress ...

Sarah Vine and Andrew Pierce bring their own no-holds-barred opinions, insights and reaction (clue is in the title) to the biggest stories of the week. New episodes every Wednesday, wherever you ...

Mesenchymal stem cells are multipotent adult stem cells that are present in multiple tissues, including umbilical cord, bone marrow and fat tissue. Mesenchymal stem cells can self-renew by ...

Background & Aims: Eosinophils are the main inflammatory effector cells that damage gastrointestinal tissue in eosinophilic gastrointestinal diseases (EGIDs). Activation of the OX40 pathway aggravates ...