We are studying the role of SLC4A11, an endothelial cell membrane transporter, in this process. We hypothesize that the SLC4A11 protein is an H+ channel. A student investigator in this project will ...

CRISPR-Cas9 technology was used to knockout the SLC4A11 gene in T cells. Results: Ammonia treatment significantly alleviated LPS-induced mastitis by reducing inflammation and inflammatory factor ...

Because the patterns of progressive sensorineural hearing loss and congenital hereditary endothelial dystrophy have both been linked to the same gene, slc4a11, we tested our patient for mutations in ...

The researchers found FECD-associated rare coding variants in 13 of the 128 Exp− patients. Four had COL8A2 variants, 2 had SLC4A11 variants, 4 had TCF4 variants (1 patient had 2 in cis), and 4 had ...

Edited by H. Ronald Kaback, University of California Los Angeles, Los Angeles, CA, and approved August 3, 2015 (received for review May 13, 2015) ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cancers display cellular, genetic and ...

This is a useful study that identifies circadian changes in the gene expression profile of cultured mouse astrocytes. Mechanistic details linking circadian rhythmicity in HERP, a regulator of calcium ...

The National Eye Institute is funding a five-year $1.95 million grant titled “Investigating the Action and Physiological Role of SLC4A11 in the Cornea.” The research focuses on the study of ...