News Medical on MSN9d
Single-cell transcriptome profiling identifies the activation of type I interferon signaling in ossified posterior longitudinal ligament
Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone ...
The Scientist9y
Single-Unit Synthetic Ribosome
Molecular biologists often tinker with the machinery of cells to figure out how they work. But for ancient machines like the ribosome, such tinkering isn’t straightforward, said Alexander Mankin ...
Nature10y
Targeted translational profiling
Tagging ribosomes ... how cells might change during development, in disease or in response to different experiences.” Initially the Heintz team attempted expression profiling of cells by using ...
eLife3d
Multi-Omics Single-Cell Analysis Reveals Key Regulators of HIV-1 Persistence and Aberrant Host Immune Responses in Early Infection
This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...
Hosted on MSN1mon
Decoding HIV's tactics: RNA structures provide new insights into how virus hijacks cells
"In this study, we combined ribosome profiling ... cleverly manipulates our cells, these discoveries will bring us closer to innovative treatments that could one day turn the tables and outsmart ...