The small airways serve as a primary line of defense against inhaled particles and facilitate gas exchange by directing air to the alveoli. These small airways are critical in the pathophysiology ...

However, we recently reported that cells expressing club cell markers (CP, LTF, MMP7, PIGR, SCGB1A1) are present in the peripheral zone of radical prostatectomy specimens. Here, expression of club ...

Pulmonary hypertension (PH) describes heterogeneous population of patients with a mean pulmonary arterial pressure >20 mm Hg. Rarely, PH presents as a primary disorder but is more commonly part of a ...

Atrial fibrillation (AF) is a highly prevalent condition that can cause or exacerbate heart failure, is an important risk factor for stroke, and is associated with pronounced morbidity and death.

A recent study posted to the bioRxiv* preprint server reported that helminth exposure enhances viral clearance and survival of mice challenged with severe acute respiratory syndrome coronavirus 2 ...

wt_tumor.data <- Read10X_h5("~/Desktop/Haake/WT_tumor/filtered_feature_bc_matrix.h5") wt_adjacent.data <- Read10X_h5("~/Desktop/Haake/WT_adjacent/filtered_feature_bc ...

Tomato (for Scgb1a1 lineage, red), CC10 (for secretory cell, white), acetylated tubulin (Act‐Tub, for ciliated cell, green), and DAPI (blue). Scale bar, 100 μm. Representative IF images of control and ...

Not only that, they showed that the immune-modulating functions of radiation therapy are due to the activation of Scgb1a1+ club cells in the lung. The researchers showed, in a mouse model of lung ...

In the study, published Sept. 20 in Nature Cancer, the researchers identified a set of anti-immunosuppressive factors that can be secreted by cells called club cells that line airways in the lungs ...