1 Department of Genetic and Biochemistry, Biological Sciences Research Unit, Peleforo GON COULIBALY University (UPGC), Korhogo, Côte d’Ivoire. 2 African Center for Shea Research and Application (CRAK) ...

The authors use a range of techniques to examine the role of Aurora Kinase A (AurA) in trained immunity. The study is hypothesis driven, it uses solid experimental approaches, and the data are ...

All peptide/kinase mixtures are diluted to a 2× working concentration in the appropriate kinase Buffer. The 2X RPS6KB1 (p70S6K)/Ser/Thr 07 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 ...

aSchool of Life Sciences, Tsinghua University, Beijing 100084, China bDepartment of Biomedical Informatics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, ...

Adult mammalian cardiomyocytes have limited proliferative capacity, but in specifically induced contexts they traverse through cell-cycle reentry, offering the potential for heart regeneration.

Breast adipose tissue is an important contributor to the obesity–breast cancer link. Extracellular vesicles (EVs) are nanosized particles containing selective cargo, such as miRNAs, that act locally ...

The latest data shows there’s a clear correlation between reduced Peripheral Blood Mononuclear Cell (PBMC) p-RPS6KB1 (B1) and p-EIF4EBP1 (P1) protein levels with the company’s monepantel (MPL) ...

Chronic autoimmune diseases are associated with mutations in PTPN22, a modifier of T cell receptor (TCR) signaling. As with all protein tyrosine phosphatases, the activity of PTPN22 is redox regulated ...

1 Laboratory of Mucosal Exposome and Biomodulation, Department of Convergence Medical Sciences, Pusan National University, Yangsan, South Korea 2 Graduate Program of Genome Data Sciences, Pusan ...

“The authors have focused on understanding the impact of a particular variant, RPS6KB1, on learning and memory and other cognitive functions in normal as well as diseased conditions.” In ...