This study presents an important finding on the role of GATA4 in aging and OA-associated cartilage pathology. The evidence supporting the conclusions is compelling, with rigorous in vitro and in vivo ...

Industry layoffs continue to accelerate, this time hitting RA Capital’s biotech incubator, according to Stat. RA Ventures, also known as Raven, is a healthcare accelerator for the prominent life ...

RA is an autoimmune disease where the immune system mistakenly attacks the lining of joints, causing inflammation and potential joint damage. Treatment goals for RA include reducing inflammation ...

Rheumatoid arthritis (RA) is an autoimmune disease that causes your body’s immune system to attack its own tissues. It causes inflammation in joints and other areas, which can lead to pain ...

As highlighted in recent advances in rheumatoid arthritis pathogenesis, researchers’ understanding of the disease has grown considerably in recent years, laying the groundwork for new ...

The search for gene therapies to treat rheumatoid arthritis (RA) has moved in fits and starts over the past two decades, with trials starting and stopping, and their focus shifting to ...

Rheumatoid arthritis (RA) is a chronic inflammatory disease that primarily affects the joints, but it can impact other organs and systems in the body, including the skin. For many people with RA ...

That was one of the key findings of a new study led by researchers at Memorial Sloan Kettering Cancer Center (MSK): The TGF-beta and RAS signaling pathways work together to spur the spread of cancer ...

A recent study showed people in their fifties with RA were more likely to exhibit cognitive deficits compared with people without the disease. People with RA and obesity had the highest risk of ...

Whether you are seeking information for yourself or a loved one, read on to learn more about the disease and how to better understand its signs and symptoms. Rheumatoid arthritis is an ...

Some people with rheumatoid arthritis (RA) can have elevated liver enzymes. This may be due to the effects of RA on the body, side effects from RA medications, or both. Having RA doesn’t always ...

In vitro experiments, we used TGF-β1 and baricitinib to stimulate human fetal lung ... Since baricitinib has been approved for the treatment of RA, which indicates this drug is safe for human [3, 4].