This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

Dr. Jay Bhattacharya, the new director of the N.I.H., announced the policy on Thursday, the same day Dr. Matthew J. Memoli, the principal deputy director, blasted these so-called subawards in an ...

Switching the bottleneck is a suggested solution to the speed problem. The experiment and simulation demonstrated that the binding of RNase H serves as the bottleneck, slowing down the entire process.

Reviewer #1 (Recommendations for the authors): The Authors characterize the combined impact of the Smc5/6 complex and RNase H in R-loop degradation. The work is solid and will provide an advance, but ...

By utilizing a combination of microRNAs (miRNAs) and the enzyme RNase H, researchers have successfully regulated the timing of droplet division. This breakthrough paves the way for creating ...

Shandong Provincial Key Laboratory of Biochemical Engineering, Qingdao Nucleic Acid Rapid Detection Engineering Research Center, Qingdao Key Laboratory of Nucleic Acid Rapid Detection, Sino-UAE ...

In contrast, ATA treatment did not further deteriorate HBV DNAs, viral proteins, and transcripts in hepatocytes transfected by an HBV RNase H dead mutant. Moreover, ATA showed an inhibitory effect on ...

Figure 1. A schematic representation of a lipid nanoparticle encapsulating mRNA. As this new form of biotechnology makes a leap of progress, so too do the analytical approaches supporting its ...

RNase L nucleolytic activity is highly effective at restricting ... This work was supported by NIH grants R21NS100182 (to S.R.W.), R01AI104887 (to S.R.W. and R.H.S.), and R01AI135922 (to R.H.S.).

Overall, while S9.6 IF microscopy approaches should probably be avoided whenever possible, any protocol should incorporate steps to destroy non‐hybrid RNA molecules and demonstrate the RNase H ...

The NEBNext RNase H-based RNA depletion protocol offers efficient and specific depletion of the abundant RNA species that interfere with the analysis of both coding and non-coding RNAs of biological ...