This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

Molecular Targets Development Program, Center for Cancer Research, National Cancer Institute, Building 1052, Room 121, Frederick, Maryland 21702-1201 * To whom correspondence should be addressed. Tel: ...

used biochemical assays to explore how the human Smc5/6 complex specifically recognizes R-loops and assists an enzyme called RNase H – which can degrade ... D8177 MATa rnh1::HIS3MX6 rnh201::kanMX6 ...

The OAS-RNase L pathway is one of the oldest innate RNA sensing pathways that leads to interferon (IFN) signaling and cell death. OAS recognizes viral RNA and then activates RNase L, which ...

We recently reported crystal structures of RNase H–RNA/DNA substrate complexes obtained at 1.5–2.2 Å. We have now determined and report here structures of reaction intermediate and product complexes ...

In this list, we will only cover the best seeds for the Minecraft Java Edition. Bedrock players can refer to our lengthy list of best Minecraft 1.19.2 Bedrock seeds from the linked article. Use the ...

Based on structure-functional studies we have designed an RNase 3/1 hybrid construct that combines the high catalytic activity of RNase 1 with RNase 3 bactericidal properties. Next, we have explored ...

Since 2015, Zika virus (ZIKV) has been recognized as a serious public health concern due to devastating birth defects caused by ZIKV infection of pregnant women. An improved understanding of ZIKV ...