Hepatocellular carcinoma (HCC), which accounts for up to 80% of cases of primary liver cancer, is typically diagnosed in an advanced stage, meaning a poor prognosis. Understanding what drives ...

Results: Using single-cell RNA sequencing, we identified significant downregulation of RGS14 in SSCs of NOA patients compared to normal testes. Immunofluorescence validation confirmed RGS14 ...

The modified mice demonstrated superior physical performance, both in speed and endurance. Mice without the RGS14 protein showed signs of delayed aging, such as less hair loss and less graying fur.

The genetically modified mice, which lack a protein called RGS14, lived around 20 per cent longer than normal mice and avoided typical signs of ageing including hair-loss and greying.

The Rutgers team has been studying a particular genetic model—mice lacking a protein called regulator of G protein signaling 14 (RGS14)—that exhibit dramatically extended lifespans and enhanced ...

The Rutgers study examined how brown fat can boost athletic performance. Mice without a protein called RGS14 live longer than others and have more brown fat. In lab tests, the long-lived mice ran ...

The discovery emerged from broader research into healthy aging. The modified mice, which lack a protein called RGS14, live about 20% longer than normal mice, with females living longer than males ...

Rutgers Health researchers have made discoveries about brown fat that may open a new path to helping people stay physically fit as they age. A team from Rutgers New Jersey Medical School found ...

The RGS14-deficient mice demonstrated several intriguing characteristics when tested on specially designed mouse treadmills. They ran significantly longer distances and performed more work before ...

One notable example involves RGS14 knockout mice, a genetically modified group known for their longer lifespan. When BAT from these mice was transplanted into regular mice, the recipients displayed ...