A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital ...

When DNA breaks inside the cell, it can spell disaster, especially if the damage occurs in areas of the genome that are difficult to repair. Now ...

When DNA breaks inside the cell, it can spell disaster, especially if the damage occurs in areas of the genome that are ...

When DNA breaks inside the cell, it can spell disaster, especially if the damage occurs in areas of the genome that are ...

BRCAness refers to tumors that mimic BRCA1/2 mutation behavior, making them vulnerable to DNA-damaging treatments like PARP ...

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

Results of a study led by the Vall d'Hebron Institute of Oncology (VHIO) support the feasibility of using RAD51 testing to complement next-generation sequencing (NGS) for precise patient ...

RAD51 is a protein involved in homologous recombination repair (HRR) alterations. Developed in-house by Serra's laboratory, the RAD51 assay is based on the detection of this protein as a ...

A particularly harmful kind of DNA damage occurs when both strands of DNA are broken. The protein RAD51 is a central player in repairing this damage — through a process called homologous recombination ...