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Too Old to Operate7mon
4-(Pyrazolyl)benzenesulfonamide Ureas as Carbonic Anhydrases Inhibitors and Hypoxia-Mediated Chemo-Sensitizing Agents in Colorectal Cancer Cells.
Hypoxia in tumors contributes to chemotherapy resistance, worsened by acidosis driven by carbonic anhydrases (CA IX and XII). Targeting these enzymes can mitigate acidosis, thus enhancing tumor ...
SciELO10mon
Substituted tridentate pyrazolyl ligands for chromium and nickel-catalyzed ethylene oligomerization reactions: effect of auxiliary ligand on activity and selectivity - SciELO
On the other hand, the introduction of relatively bulky phenyl substituents at 5-position of the pyrazolyl rings in 2a as compared to methyl groups in CrCl 3 ...
Frontiers2y
Corrigendum: Pyrazolyl-s-triazine with indole motif as a novel of epidermal growth factor receptor/cyclin-dependent kinase 2 dual inhibitors - Frontiers
Keywords: pyrazolyl-s-triazine, indole, anticancer profile, EGFR/CDK-2, apoptosis Citation: Shawish I, Nafie MS, Barakat A, Aldalbahi A, Al-Rasheed HH, Ali M, Alshaer W, Al Zoubi M, Al Ayoubi S, De La ...
Scientific Research Publishing4y
Syntheses and Characterization of Two Novel Copper (II) Malonate Complexes Functionalized with 3,3’-Bis (pyrazolyl)pentane and 4,4’-Trimethylenedipyridine
Abstract. Two novel copper complexes (1,2) with N,O-donor ligands were synthesized by reaction of copper(II) malonates with 3,3’-bis(pyrazolyl)pentane and 4,4’-trimethylenedipyridine in methanol at ...
Scientific Research Publishing13y
Reactivity of 1-methylisoquinoline synthesis of pyrazolyl triazoloisoquinoline and thia-diazolyl isoquinoline derivatives - Scientific Research Publishing
Product 4 reacts with dimethylformamide-dimethylacetal to give ena- minones 7 which react with hydrazonoyl halides to give pyrazolyl triazoloisoquinoline 13. Also, 1-methylisoquinoline 1 reacts with ...