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In October 2012, one of the largest and most destructive storms to emerge from the Atlantic devastated the US and Caribbean.
New research suggests that Huntington’s disease could cause the brain to rewire, like a road detour. While connections between some brain cells are shut down, the traffic seems to get re-routed, ...
A new neuroimaging study published in Molecular Psychiatry provides evidence that anorexia nervosa is associated with altered ...
Long-term safety follow-up will continue to Year 15. Study Procedure and Results Administration of the DANPCs into the posterior putamen was performed with participants under general anesthesia.
Five patients received a low-dose (0.9 million cells per putamen) and seven received a high-dose (2.7 million cells per putamen), coupled with 1 year of immunosuppression. The trial achieved its ...
Twelve patients with a median age of 67 received surgical transplantation of bemdaneprocel to the putamen on both sides of the brain. Five participants received a low dose (0.9 million cells per ...
Brain imaging showed atrophy in the caudate and putamen at this time point. A longitudinal increase in the somatic cytosine-adenine-guanine repeat expansion ratio in blood predicted brain atrophy.
The basal ganglia are made up of three main parts, the caudate nucleus, the putamen, and the globus pallidus. Benign essential tremor: A condition characterized by tremor of the hands, head ...
A new PET ligand, C05-05, binds α-synuclein fibrils. It lit up the midbrain in PD and DLB; the putamen and cerebellum in MSA. High midbrain C05-05 uptake correlated with worse motor symptoms. “That ...
ASt=amygdalostrital transition zone. Pu=Putamen. Cl=Claustrum. Image Credit: University of Turku Stuttering is a speech rhythm disorder characterized by involuntary repetitions, prolongations or ...
The study met its primary objective, which was to evaluate the safety of a one-time bilateral delivery of AB-1005 directly to the putamen. Eleven patients were enrolled into two cohorts ...
The phase 1b study of gene therapy AB-1005 met the key primary endpoint of safety, showing that the one-time medicine can be delivered to the putamen region of the brain, according to a Thursday ...