Frontiers1y
The effects of gonadotropin-releasing hormone agonist on final adult height among girls with early and fast puberty
The inclusion criteria were as follows: (1) girls with breast Tanner stage 2 with or without pubic hair between 7 and 10 years; (2) a basal serum luteinizing hormone (LH) level ≧0.3 IU/L or peak LH ...
eLife4y
Highly redundant neuropeptide volume co-transmission underlying episodic activation of the GnRH neuron dendron
only kisspeptin was able to activate the GnRH neuron dendron. Mice with a selective deletion of kisspeptin from KNDy neurons failed to exhibit pulsatile hormone secretion but maintained synchronized ...
eLife6y
NKB signaling in the posterodorsal medial amygdala stimulates gonadotropin release in a kisspeptin-independent manner in female mice
Neurokinin B (NKB) signaling is critical for reproduction in all studied species. The existing consensus is that NKB induces GnRH release via kisspeptin (Kiss1) stimulation in the arcuate nucleus.
Frontiers10y
The role of GABA in the regulation of GnRH neurons
Gonadotropin-releasing hormone (GnRH) neurons constitute the final output neurons in the neuroendocrine control of reproduction (Freeman, 2006). Pulsatile GnRH release stimulates the secretion of the ...