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TITLE: Manifestation of Pathological States of Numerous Diseases in the Largest Organ of the Human Body: (II) From Pancreatitis to Pancreatic Cancer Invasion, Formation of Stroma around the Primary ...
The first patient, with no history of skin cancer, was shown to have a .8 x 1.5-cm smooth pearly nodule with rolled borders and arborizing telangiectasias on his right temple. In Case #2, the patient ...
Phosphorylation‐linked complex profiling identifies assemblies required for Hippo signal integration
We detected a PTPN14/LATS1/YAP1 complex and suggest a model how PTPN14 inhibits YAP1 via augmenting WW domain‐dependent complex formation and phosphorylation by LATS1/2. A novel approach is proposed ...
Pseudophosphatases in non-receptor PTPs include non-receptor tyrosine protein kinase 23 (HD-PTP/PTPN23), non-receptor tyrosine protein kinase 14 (PTPN14) and non-receptor tyrosine protein kinase 21 ...
Hence, the aim of this review is to summarize the role played by PTPNs, including PTPN1/PTP1B, PTPN2/TC-PTP, PTPN3/PTP-H1, PTPN4/PTPMEG, PTPN6/SHP-1, PTPN9/PTPMEG2, PTPN11/SHP-2, PTPN12/PTP-PEST, ...
YAP1 activation by HPV E7 required that E7 binds and degrades the tumor suppressor protein tyrosine phosphatase non-receptor type 14 (PTPN14). E7 required YAP1 transcriptional activity to extend the ...
Decision letter after peer review: Thank you for submitting your article "YAP1 activation by human papillomavirus E7 promotes basal cell identity in squamous epithelia" for consideration by eLife.
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