Researchers have identified a gene that plays a key role in prostate cancer cells that have transitioned to a more aggressive, treatment-resistant form. The gene can be indirectly targeted with an ...

Researchers at the University of Michigan Health Rogel Cancer Center identified a gene that plays a key role in prostate ...

Researchers at the University of Michigan Rogel Cancer Center identified a gene that plays a key role in prostate cancer ...

During the experiment, scientists progressively removed a protein called PROX1 from the mice – a protein that blocks the restoration of retinal cells. The researchers noted the adverse effects ...

For now though, it's only been tested in mice. Here's how it works: a compound antibody drug is used to block the prospero homeobox protein 1 (Prox1). This protein isn't inherently bad, playing an ...

Schematic diagram of the mechanism of retinal regeneration through inhibition of PROX1 migration. Credit: Nature Communications, 2025. Inside our eyes, a special kind of cell called Müller glia ...

This treatment works by blocking the PROX1 protein, a key inhibitor of retinal regeneration, and has shown lasting effects in mouse models of retinal disease. Blocking the PROX1 protein allowed KAIST ...

The research team successfully induced retinal regeneration and vision recovery in a disease-model mouse by administering a compound that blocks the PROX1 (prospero homeobox 1) protein ...

The research team successfully induced neural regeneration and vision recovery in a disease-model mouse by administering a compound that blocks the PROX1 (Prospero Homeobox 1) protein, which ...

The research team successfully induced retinal regeneration and vision recovery in a disease-model mouse by administering a compound that blocks the PROX1 (prospero homeobox 1) protein ...