Finally, immunohistochemical staining was carried out on self-collected clinical samples to assess PITX1 expression levels and correlate them with clinical information. Results: Gene differential ...

For instance, we discovered novel roles of key genes MSC and PITX1 that may regulate muscle stem cells. This could offer potential for treating muscle-related disorders or injuries." More ...

1 Affiliated Hospital of Weifang Medical University, School of Clinical Medicine, Weifang Medical University, Weifang, Shandong, China 2 Abdominal Oncology Ward, Cancer Center, West China Hospital of ...

Endothelial dysfunction enhances vascular inflammation, which initiates pulmonary arterial hypertension (PAH) pathogenesis, further induces vascular remodeling and right ventricular failure.

By studying the Pitx1 gene, one of the genes involved in the construction of the lower limbs, a team has discovered how a small disturbance in the activation process of this gene is at the origin ...

By studying the Pitx1 gene, one of the genes involved in the construction of the lower limbs, a team from the University of Geneva (UNIGE), in Switzerland, has discovered how a small disturbance ...

Fluorescence visualisation of Pitx1 gene expression in mouse embryos. The absence of Pen, one of the Pitx1 switches (right), results in a loss of fluorescence in developing legs. (© UNIGE / Guillaume ...

“However, could the loss of one of these switches have consequences? This is what we wanted to test here by taking as a model the Pitx1 gene, whose role in the construction of the lower limbs is well ...

ABSTRACT: Genomic analysis has emphasized the enormous genetic contribution to autism spectrum disorders, with over 80% of patients having changes demonstrable by high resolution chromosome ...

The trachea or windpipe is a tube that connects the throat to the lungs, while the esophagus connects the throat to the stomach. The trachea has cartilage rings that help to ensure clear airflow to ...

Previous work had demonstrated that regulatory mutations in the genes Tbx5 and Pitx1 contribute to foot feathering in domesticated breeds of pigeon. Bortoluzzi wanted to investigate whether ...